Total number of Results for c.404G>C,p.Arg135Thr are 38
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0948 UGCAAAAUCUUAAUGAUAC
ACGUUUUAGAAUUACUAUG		 45 30 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0949 GCAAAAUCUUAAUGAUACA
CGUUUUAGAAUUACUAUGU		 35 45 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0950 CAAAAUCUUAAUGAUACAU
GUUUUAGAAUUACUAUGUA		 82 20 62 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0951 AAAAUCUUAAUGAUACAUU
UUUUAGAAUUACUAUGUAA		 10 20 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0952 AAAUCUUAAUGAUACAUUA
UUUAGAAUUACUAUGUAAU		 40 40 0 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0953 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC		 79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0954 AUCUUAAUGAUACAUUAGC
UAGAAUUACUAUGUAAUCG		 83 50 33 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0955 UCUUAAUGAUACAUUAGCU
AGAAUUACUAUGUAAUCGA		 90 45 45 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0956 CUUAAUGAUACAUUAGCUU
GAAUUACUAUGUAAUCGAA		 41 40 1 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0957 UUAAUGAUACAUUAGCUUC
AAUUACUAUGUAAUCGAAG		 60 20 40 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0958 UAAUGAUACAUUAGCUUCC
AUUACUAUGUAAUCGAAGG		 90 0 90 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0959 AAUGAUACAUUAGCUUCCU
UUACUAUGUAAUCGAAGGA		 88 10 78 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0960 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU		 92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0961 UGAUACAUUAGCUUCCUAC
ACUAUGUAAUCGAAGGAUG		 90 56 34 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0962 GAUACAUUAGCUUCCUACC
CUAUGUAAUCGAAGGAUGG		 30 20 10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0963 AUACAUUAGCUUCCUACCU
UAUGUAAUCGAAGGAUGGA		 10 25 -15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0964 UACAUUAGCUUCCUACCUG
AUGUAAUCGAAGGAUGGAC		 20 30 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0965 ACAUUAGCUUCCUACCUGG
UGUAAUCGAAGGAUGGACC		 60 30 30 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna0966 CAUUAGCUUCCUACCUGGA
GUAAUCGAAGGAUGGACCU		 36 60 -24 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3509 UGCAAAAUCUUAAUGAUAC
ACGUUUUAGAAUUACUAUG		 45 30 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3510 GCAAAAUCUUAAUGAUACA
CGUUUUAGAAUUACUAUGU		 35 20 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3511 CAAAAUCUUAAUGAUACAU
GUUUUAGAAUUACUAUGUA		 82 33 49 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3512 AAAAUCUUAAUGAUACAUU
UUUUAGAAUUACUAUGUAA		 10 20 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3513 AAAUCUUAAUGAUACAUUA
UUUAGAAUUACUAUGUAAU		 40 40 0 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3514 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC		 79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3515 AUCUUAAUGAUACAUUAGC
UAGAAUUACUAUGUAAUCG		 83 50 33 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3516 UCUUAAUGAUACAUUAGCU
AGAAUUACUAUGUAAUCGA		 90 45 45 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3517 CUUAAUGAUACAUUAGCUU
GAAUUACUAUGUAAUCGAA		 41 20 21 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3518 UUAAUGAUACAUUAGCUUC
AAUUACUAUGUAAUCGAAG		 60 20 40 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3519 UAAUGAUACAUUAGCUUCC
AUUACUAUGUAAUCGAAGG		 90 0 90 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3520 AAUGAUACAUUAGCUUCCU
UUACUAUGUAAUCGAAGGA		 88 10 78 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3521 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU		 92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3522 UGAUACAUUAGCUUCCUAC
ACUAUGUAAUCGAAGGAUG		 90 56 34 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3523 GAUACAUUAGCUUCCUACC
CUAUGUAAUCGAAGGAUGG		 30 20 10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3524 AUACAUUAGCUUCCUACCU
UAUGUAAUCGAAGGAUGGA		 10 25 -15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3525 UACAUUAGCUUCCUACCUG
AUGUAAUCGAAGGAUGGAC		 20 30 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3526 ACAUUAGCUUCCUACCUGG
UGUAAUCGAAGGAUGGACC		 60 30 30 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3527 CAUUAGCUUCCUACCUGGA
GUAAUCGAAGGAUGGACCU		 36 30 6 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254